You should know that your mental health may change in unexpected ways when you take bupropion or other antidepressants even if you are an adult over age 24 or if you do not have a mental illness and you are taking bupropion to treat a different type of condition. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased.
You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.
Your health care provider will want to see you often while you are taking bupropion, especially at the beginning of your treatment. Be sure to keep all appointments or office visits with your doctor. Your doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin treatment with bupropion and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. Bupropion Aplenzin, Wellbutrin XL is also used to treat seasonal affective disorder SAD; episodes of depression that occur at the same time each year [usually in the fall and winter but rarely may occur in the spring or summer months].
Bupropion Zyban is used to help people stop smoking. Bupropion is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain. Bupropion comes as a tablet and a sustained-release or extended-release long-acting tablet to take by mouth.
The regular tablet Wellbutrin is usually taken three times a day, with doses at least 6 hours apart, or four times a day, with doses at least 4 hours apart. The sustained-release tablet Wellbutrin SR, Zyban is usually taken twice a day, with doses at least 8 hours apart. The extended-release tablet Aplenzin, Wellbutrin XL is usually taken once daily in the morning; doses of the extended-release tablet should be taken at least 24 hours apart.
When bupropion is used to treat seasonal affective disorder, it is usually taken once a day in the morning beginning in the early fall, continuing through the winter, and stopping in the early spring. Sometimes a lower dose of bupropion is taken for 2 weeks before the medication is stopped. Take bupropion with food if the medication upsets your stomach. If you have trouble falling asleep or staying asleep, do not take bupropion too close to bedtime.
Take bupropion at around the same time s every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take bupropion exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the sustained-release and extended-release tablets whole; do not split, chew, or crush them. It may take 4 weeks or longer before you feel the full benefit of bupropion.
Wellbutrin requires a prescription. It can take weeks before you start to see an improvement. After 3 months you should feel the full benefits. NDRIs increase the level of dopamine and norepinephrine in the brain.
Services Mental Health Anxiety Popular. Depression Popular. Insomnia Popular. Bupropion has also been evaluated for smoking cessation during pregnancy and is recommended only after other therapies have failed. Bupropion hydrochloride is available in 3 different forms: immediate release IR , sustained release SR , and extended release XL. Bupropion IR is usually taken 2 or 3 times per day with hours between doses.
The dose usually ranges from mg twice daily to mg three times daily, with the last dose taken mid-afternoon. Bupropion SR is usually taken twice daily in the morning and mid-afternoon. The dose usually ranges from mg twice daily up to mg twice daily. The dose ranges from mg to mg.
While there are dose ranges for each form, your health care provider will determine the form and dose that is right for you based on your response. The dose may be increased to mg once daily. The dose for smoking cessation is bupropion SR mg once daily for 3 days and then twice daily for 7 to 12 weeks. You should not take more than one product that contains bupropion, including the products that are used to quit smoking.
Do not take more than your prescribed dose since higher doses may increase your risk of having a seizure. Since quickly increasing the dose of bupropion can cause seizures in some people, your doctor will slowly increase your dose. You can take bupropion on an empty stomach or with food. The SR and XL forms should be swallowed whole — not chewed, crushed, or broken — so that the medication can work correctly in your body and to reduce the risk of serious side effects. The tablet shell from the SR and XL forms may appear in your feces.
Consider using a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member or friend to remind you or check in with you to be sure you are taking your medication.
For bupropion IR or SR, if you miss a dose, take it as soon as you remember. Take the remaining doses for the day at evenly spaced times at least 4 hours apart.
DO NOT take 2 doses at once. You should not take more than your prescribed dose and doing so may increase your risk of having a seizure. For bupropion XL, do not take an extra tablet to make up for the dose you forgot. Wait and take your next dose at your regular time the next day. Avoid drinking alcohol or using illegal drugs while you are taking bupropion because the beneficial effects of the medication may be decreased and the risk of seizures may be increased.
If you are dependent on drugs or alcohol and would like to stop, consult your healthcare provider for help. Abruptly stopping these substances can result in a seizure, especially when taking bupropion.
If an overdose occurs, call your doctor or You may need urgent medical care. You may also contact the poison control center at It is one of the most frequently prescribed antidepressants in the English-speaking world. It is mainly used to treat and prevent depression and as a smoking cessation aid.
It is less likely to cause weight gain or sexual dysfunction than an SSRI, but it can trigger seizures in those who are susceptible. Most antidepressants are selective serotonin reuptake inhibitor SSRI. They boost the levels of serotonin in the brain. Bupropion, or Wellbutrin, is different. It is a norepinephrine-dopamine reuptake inhibitor NDRI. An NDRI boosts levels of the neurotransmitters norepinephrine, also known as noradrenaline, and dopamine.
As well as being an antidepressant, bupropion is an antagonist at nicotinic receptors. This means that it blocks receptors where nicotine normally binds, making it useful in smoking cessation. Wellbutrin is taken by mouth as a milligram mg tablet, a mg tablet, or a mg extended release XR tablet. The mg XR tablet is more popular.
A person who is using the mg SR tablet will take one tablet twice a day. No single dose should exceed mg, and the daily dose should not exceed mg. The tablet should be taken in the morning and, in the case of the XR tablet, swallowed whole. Breaking or chewing an XR tablet increases the risk of an overdose, and possibly seizures. Wellbutrin has been trialed for use in ADHD , weight loss, and bipolar depression, but, so far, significant evidence only supports depression and smoking cessation. Wellbutrin has been found to be at least as effective as other popularly prescribed antidepressant medication.
There is also less chance of weight gain, sleepiness, and sexual dysfunction than with other forms of treatment. It may even work actively against sexual dysfunction resulting from previous antidepressant use.
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